The Development of Psoriasis Over a Silicone Granuloma: Case Report and Postulated Mechanism of Pathogenesis

Liquid silicone injections are used for soft tissue augmentation and have the potential to cause adverse effects. A 60-year-old woman who developed a psoriatic lesion over a silicone granuloma is reported. The clinical, dermatoscopic, and histological findings were characteristic of psoriasis. The p...

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Autores principales: Rosales Santillan, Monica, Silapunt, Sirunya, Tschen, Jaime A, Cohen, Philip R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059527/
https://www.ncbi.nlm.nih.gov/pubmed/30050739
http://dx.doi.org/10.7759/cureus.2684
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author Rosales Santillan, Monica
Silapunt, Sirunya
Tschen, Jaime A
Cohen, Philip R
author_facet Rosales Santillan, Monica
Silapunt, Sirunya
Tschen, Jaime A
Cohen, Philip R
author_sort Rosales Santillan, Monica
collection PubMed
description Liquid silicone injections are used for soft tissue augmentation and have the potential to cause adverse effects. A 60-year-old woman who developed a psoriatic lesion over a silicone granuloma is reported. The clinical, dermatoscopic, and histological findings were characteristic of psoriasis. The patient was started on hydroxychloroquine for the treatment of the granuloma without any subsequent development of new psoriatic lesions. The presentation of psoriasis associated with a silicone granuloma in an immunocompetent patient is unique. The sequence of events is another example of a dermatosis occurring in an immunocompromised cutaneous district.
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spelling pubmed-60595272018-07-26 The Development of Psoriasis Over a Silicone Granuloma: Case Report and Postulated Mechanism of Pathogenesis Rosales Santillan, Monica Silapunt, Sirunya Tschen, Jaime A Cohen, Philip R Cureus Dermatology Liquid silicone injections are used for soft tissue augmentation and have the potential to cause adverse effects. A 60-year-old woman who developed a psoriatic lesion over a silicone granuloma is reported. The clinical, dermatoscopic, and histological findings were characteristic of psoriasis. The patient was started on hydroxychloroquine for the treatment of the granuloma without any subsequent development of new psoriatic lesions. The presentation of psoriasis associated with a silicone granuloma in an immunocompetent patient is unique. The sequence of events is another example of a dermatosis occurring in an immunocompromised cutaneous district. Cureus 2018-05-24 /pmc/articles/PMC6059527/ /pubmed/30050739 http://dx.doi.org/10.7759/cureus.2684 Text en Copyright © 2018, Rosales Santillan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Rosales Santillan, Monica
Silapunt, Sirunya
Tschen, Jaime A
Cohen, Philip R
The Development of Psoriasis Over a Silicone Granuloma: Case Report and Postulated Mechanism of Pathogenesis
title The Development of Psoriasis Over a Silicone Granuloma: Case Report and Postulated Mechanism of Pathogenesis
title_full The Development of Psoriasis Over a Silicone Granuloma: Case Report and Postulated Mechanism of Pathogenesis
title_fullStr The Development of Psoriasis Over a Silicone Granuloma: Case Report and Postulated Mechanism of Pathogenesis
title_full_unstemmed The Development of Psoriasis Over a Silicone Granuloma: Case Report and Postulated Mechanism of Pathogenesis
title_short The Development of Psoriasis Over a Silicone Granuloma: Case Report and Postulated Mechanism of Pathogenesis
title_sort development of psoriasis over a silicone granuloma: case report and postulated mechanism of pathogenesis
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059527/
https://www.ncbi.nlm.nih.gov/pubmed/30050739
http://dx.doi.org/10.7759/cureus.2684
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