Cargando…

Hypothermic machine perfusion attenuates ischemia/reperfusion injury against rat livers donated after cardiac death by activating the Keap1/Nrf2-ARE signaling pathway

Hypothermic machine perfusion (HMP) has been demonstrated to be a more effective method for preserving livers donated after circulatory death (DCD) than cold storage (CS); however, the underlying mechanisms remain unclear. The aim of the present study was to investigate the protective effects of HMP...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xue, Shuai, He, Weiyang, Zeng, Xianpeng, Tang, Zimei, Feng, Shoucheng, Zhong, Zibiao, Xiong, Yan, Wang, Yanfeng, Ye, Qifa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059711/ https://www.ncbi.nlm.nih.gov/pubmed/29845199 http://dx.doi.org/10.3892/mmr.2018.9065

Ejemplares similares

Appropriate timing for hypothermic machine perfusion to preserve livers donated after circulatory death
por: Hu, Xiaoyan, et al.
Publicado: (2020)

Hypothermic machine perfusion increases A20 expression which protects renal cells against ischemia/reperfusion injury by suppressing inflammation, apoptosis and necroptosis
por: YANG, ZIXUAN, et al.
Publicado: (2016)

Hypothermic machine perfusion ameliorates inflammation during ischemia-reperfusion injury via sirtuin-1-mediated deacetylation of nuclear factor-κB p65 in rat livers donated after circulatory death
por: Zeng, Cheng, et al.
Publicado: (2017)

Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury
por: Zhou, Wei, et al.
Publicado: (2021)

Correction: Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury
por: Zhou, Wei, et al.
Publicado: (2021)

A novel hypothermic machine perfusion system using a LifePort Kidney Transporter for the preservation of rat liver
por: Zeng, Cheng, et al.
Publicado: (2018)

The Effect of Hypothermic Machine Perfusion to Ameliorate Ischemia-Reperfusion Injury in Donor Organs
por: Knijff, Laura W. D., et al.
Publicado: (2022)

Hypothermic machine perfusion alleviates ischemia-reperfusion injury of intestinal transplantation in pigs
por: Hou, Wen, et al.
Publicado: (2023)

Roles of TRAFs in Ischemia-Reperfusion Injury
por: Zhou, Wei, et al.
Publicado: (2020)

Hypothermic oxygenated perfusion attenuates DCD liver ischemia–reperfusion injury by activating the JAK2/STAT3/HAX1 pathway to regulate endoplasmic reticulum stress
por: Yue, Pengpeng, et al.
Publicado: (2023)

Vagus Nerve Stimulation Alleviates Hepatic Ischemia and Reperfusion Injury by Regulating Glutathione Production and Transformation
por: Xia, Haoyang, et al.
Publicado: (2020)

Gypenoside attenuates hepatic ischemia/reperfusion injury in mice via anti-oxidative and anti-apoptotic bioactivities
por: ZHAO, JIE, et al.
Publicado: (2014)

Hypothermic oxygenated machine perfusion reduces bile duct reperfusion injury after transplantation of donation after circulatory death livers
por: van Rijn, Rianne, et al.
Publicado: (2018)

Evaluation Using an Isolated Reperfusion Model for Porcine Liver Donated After Cardiac Death Preserved with Oxygenated Hypothermic Machine Perfusion
por: Yoshikawa, Ryo, et al.
Publicado: (2018)

Pharmacological Protection against Ischemia-Reperfusion Injury by Regulating the Nrf2-Keap1-ARE Signaling Pathway
por: Ucar, Bercis Imge, et al.
Publicado: (2021)

Ischemia-Reperfusion Injury in Marginal Liver Grafts and the Role of Hypothermic Machine Perfusion: Molecular Mechanisms and Clinical Implications
por: Czigany, Zoltan, et al.
Publicado: (2020)

Subnormothermic ex vivo lung perfusion attenuates ischemia reperfusion injury from donation after circulatory death donors
por: Arni, Stephan, et al.
Publicado: (2021)

Dual hypothermic oxygenated machine perfusion in liver transplants donated after circulatory death
por: van Rijn, R., et al.
Publicado: (2017)

SIRT3 a Major Player in Attenuation of Hepatic Ischemia-Reperfusion Injury by Reducing ROS via Its Downstream Mediators: SOD2, CYP-D, and HIF-1α
por: Katwal, Gaurav, et al.
Publicado: (2018)

Mild Hypothermia Attenuates Hepatic Ischemia–Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation
por: Wang, Wei, et al.
Publicado: (2020)

Pretreatment with Panaxatriol Saponin Attenuates Mitochondrial Apoptosis and Oxidative Stress to Facilitate Treatment of Myocardial Ischemia-Reperfusion Injury via the Regulation of Keap1/Nrf2 Activity
por: Yao, Huan, et al.
Publicado: (2022)

Role of Keap1-Nrf2/ARE signal transduction pathway in protection of dexmedetomidine preconditioning against myocardial ischemia/reperfusion injury
por: Li, Hui-xian, et al.
Publicado: (2022)

Simply Adding Oxygen during Hypothermic Machine Perfusion to Combat the Negative Effects of Ischemia-Reperfusion Injury: Fundamentals and Current Evidence for Kidneys
por: Darius, Tom, et al.
Publicado: (2021)

Hypothermic Oxygenated Machine Perfusion Prevents Arteriolonecrosis of the Peribiliary Plexus in Pig Livers Donated after Circulatory Death
por: op den Dries, Sanna, et al.
Publicado: (2014)

Mitoquinone Alleviates Donation after Cardiac Death Kidney Injury during Hypothermic Machine Perfusion in Rat Model
por: Radajewska, Anna, et al.
Publicado: (2023)

Lipoxin A4 Preconditioning Attenuates Intestinal Ischemia Reperfusion Injury through Keap1/Nrf2 Pathway in a Lipoxin A4 Receptor Independent Manner
por: Han, Xue, et al.
Publicado: (2016)

Normothermic Regional Perfusion and Hypothermic Oxygenated Machine Perfusion for Livers Donated After Controlled Circulatory Death With Prolonged Warm Ischemia Time: A Matched Comparison With Livers From Brain-Dead Donors
por: Patrono, Damiano, et al.
Publicado: (2022)

Pretreatment with the ALDH2 activator Alda-1 protects rat livers from ischemia/reperfusion injury by inducing autophagy
por: Liu, Zhongzhong, et al.
Publicado: (2020)

Astragaloside IV protects against ischemia/reperfusion (I/R)-induced kidney injury based on the Keap1-Nrf2/ARE signaling pathway
por: Su, Yanyan, et al.
Publicado: (2022)

Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue
por: Han, Guo-Jie, et al.
Publicado: (2022)

Effects of SP600125 and hypothermic machine perfusion on livers donated after cardiac death in a pig allograft transplantation model
por: Zhang, Yijie, et al.
Publicado: (2021)

Sweroside Protects Against Myocardial Ischemia–Reperfusion Injury by Inhibiting Oxidative Stress and Pyroptosis Partially via Modulation of the Keap1/Nrf2 Axis
por: Li, Jun, et al.
Publicado: (2021)

The Regulatory Effects of JAK2/STAT3 on Spermatogenesis and the Redox Keap1/Nrf2 Axis in an Animal Model of Testicular Ischemia Reperfusion Injury
por: Alnajem, Abdullah, et al.
Publicado: (2023)

FGF18 alleviates hepatic ischemia-reperfusion injury via the USP16-mediated KEAP1/Nrf2 signaling pathway in male mice
por: Tong, Gaozan, et al.
Publicado: (2023)

Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat
por: Liu, Zhongzhong, et al.
Publicado: (2017)

Activation of Nrf2 Signaling by Apelin Attenuates Renal Ischemia Reperfusion Injury in Diabetic Rats
por: Zhang, Xiaobo, et al.
Publicado: (2020)

Sevoflurane attenuates hepatic ischemia reperfusion injury by the miR-122/Nrf2 pathway
por: Zhang, Kai, et al.
Publicado: (2022)

Decrease of renal resistance during hypothermic oxygenated machine perfusion is associated with early allograft function in extended criteria donation kidney transplantation
por: Meister, Franziska A., et al.
Publicado: (2020)

Git1-PGK1 interaction achieves self-protection against spinal cord ischemia-reperfusion injury by modulating Keap1/Nrf2 signaling
por: Xu, Tao, et al.
Publicado: (2023)

Comprehensive circRNA expression profile during ischemic postconditioning attenuating hepatic ischemia/reperfusion injury
por: Zhang, Pengpeng, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8eftpfscjbfj2hpeq3uhglu1qc