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Human β-defensin 2 kills Candida albicans through phosphatidylinositol 4,5-bisphosphate–mediated membrane permeabilization

Human defensins belong to a subfamily of the cationic antimicrobial peptides and act as a first line of defense against invading microbes. Their often broad-spectrum antimicrobial and antitumor activities make them attractive for therapeutic development; however, their precise molecular mechanism(s)...

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Detalles Bibliográficos
Autores principales:	Järvå, Michael, Phan, Thanh Kha, Lay, Fung T., Caria, Sofia, Kvansakul, Marc, Hulett, Mark D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059731/ https://www.ncbi.nlm.nih.gov/pubmed/30050988 http://dx.doi.org/10.1126/sciadv.aat0979

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