Cargando…

Downregulation of RPN2 induces apoptosis and inhibits migration and invasion in colon carcinoma

The morbidity of colorectal cancer (CRC) increases annualy, which accounts to higher mortality worldwide. Therefore, it is important to study the pathogenesis of colon cancer. Ribophorin II (RPN2), part of the N-oligosaccharyltransferase complex, is highly expressed in CRC. In the present study, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bi, Chongyao, Jiang, Baofei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059750/ https://www.ncbi.nlm.nih.gov/pubmed/29749494 http://dx.doi.org/10.3892/or.2018.6434

Ejemplares similares

Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets
por: Lu, Xiuxiu, et al.
Publicado: (2017)

Downregulation of SUMO2 inhibits hepatocellular carcinoma cell proliferation, migration and invasion
por: Chen, Jintu, et al.
Publicado: (2021)

Downregulation of VEGFA inhibits proliferation, promotes apoptosis, and suppresses migration and invasion of renal clear cell carcinoma
por: Zeng, Fan-Chang, et al.
Publicado: (2016)

Anlotinib inhibits the proliferation, migration and invasion, and induces apoptosis of breast cancer cells by downregulating TFAP2C
por: Fang, Fuxiao, et al.
Publicado: (2022)

Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12
por: Riedinger, Christiane, et al.
Publicado: (2010)

Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis
por: Hamazaki, Jun, et al.
Publicado: (2015)

Tenacissoside H Induces Apoptosis and Inhibits Migration of Colon Cancer Cells by Downregulating Expression of GOLPH3 Gene
por: Hong, Zhong-Shi, et al.
Publicado: (2020)

Downregulation of LIMK1–ADF/cofilin by DADS inhibits the migration and invasion of colon cancer
por: Su, Jian, et al.
Publicado: (2017)

Reversine inhibits proliferation, invasion and migration and induces cell apoptosis in gastric cancer cells by downregulating TTK
por: Xia, Pengfei, et al.
Publicado: (2021)

Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporation
por: Boehringer, Jonas, et al.
Publicado: (2012)

Mechanism of the Rpn13-induced activation of Uch37
por: Jiao, Lianying, et al.
Publicado: (2014)

RPN2 expression predicts response to docetaxel in oesophageal squamous cell carcinoma
por: Kurashige, J, et al.
Publicado: (2012)

A High Affinity hRpn2-Derived Peptide That Displaces Human Rpn13 from Proteasome in 293T Cells
por: Lu, Xiuxiu, et al.
Publicado: (2015)

RPN2 promotes metastasis of hepatocellular carcinoma cell and inhibits autophagy via STAT3 and NF-κB pathways
por: Huang, Linsheng, et al.
Publicado: (2019)

Downregulation of miR-552 in hepatocellular carcinoma inhibits cell migration and invasion, and promotes cell apoptosis via RUNX3
por: Ma, Ying, et al.
Publicado: (2019)

Downregulation of PITX2 inhibits the proliferation and migration of liver cancer cells and induces cell apoptosis
por: Tuerxun, Kebinuer, et al.
Publicado: (2021)

MicroRNA-128 targeting RPN2 inhibits cell proliferation and migration through the Akt-p53-cyclin pathway in colorectal cancer cells
por: Zhou, Taicheng, et al.
Publicado: (2018)

Downregulation of CLDN6 inhibits cell migration and invasion and promotes apoptosis by regulation of the JAK2/STAT3 signaling pathway in hepatocellular carcinoma
por: He, Zhiyi, et al.
Publicado: (2023)

Downregulation of BRAF-activated non-coding RNA suppresses the proliferation, migration and invasion, and induces apoptosis of hepatocellular carcinoma cells
por: Li, Jing, et al.
Publicado: (2017)

PRAF3 induces apoptosis and inhibits migration and invasion in human esophageal squamous cell carcinoma
por: Shi, Guo-Zhen, et al.
Publicado: (2012)

Downregulation of miR-222 Induces Apoptosis and Cellular Migration in Adenoid Cystic Carcinoma Cells
por: Zhou, Ziliang, et al.
Publicado: (2017)

Polydatin inhibits cell proliferation, invasion and migration, and induces cell apoptosis in hepatocellular carcinoma
por: Jiao, Yang, et al.
Publicado: (2018)

Benzyl-isothiocyanate Induces Apoptosis and Inhibits Migration and Invasion of Hepatocellular Carcinoma Cells in vitro
por: Zhu, Mingyue, et al.
Publicado: (2017)

Downregulation of SHCBP1 Inhibits Proliferation, Migration, and Invasion in Human Nasopharyngeal Carcinoma Cells
por: Zhang, Tian, et al.
Publicado: (2021)

Small interfering RNA-mediated downregulation of β-catenin inhibits invasion and migration of colon cancer cells in vitro
por: Han, Jianjun, et al.
Publicado: (2012)

Retracted: Downregulation of SHCBP1 Inhibits Proliferation, Migration, and Invasion in Human Nasopharyngeal Carcinoma Cells
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Verteporfin Promotes the Apoptosis and Inhibits the Proliferation, Migration, and Invasion of Cervical Cancer Cells by Downregulating SULT2B1 Expression
por: Yin, Lijun, et al.
Publicado: (2020)

Downregulation of lncRNA RPLP0P2 inhibits cell proliferation, invasion and migration, and promotes apoptosis in colorectal cancer
por: Yuan, Hang, et al.
Publicado: (2021)

Knockdown MTDH Inhibits Glioma Proliferation and Migration and Promotes Apoptosis by Downregulating MYBL2
por: Fu, Junqi, et al.
Publicado: (2022)

KLF2 Inhibits the Migration and Invasion of Prostate Cancer Cells by Downregulating MMP2
por: Wang, Binshuai, et al.
Publicado: (2018)

Downregulation of hsa-miR-135b-5p Inhibits Cell Proliferation, Migration, and Invasion in Colon Adenocarcinoma
por: Zhang, Yunxin, et al.
Publicado: (2022)

Hydroxycamptothecin induces apoptosis and inhibits tumor growth in colon cancer by the downregulation of survivin and XIAP expression
por: Fei, Bojian, et al.
Publicado: (2013)

Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer
por: Anchoori, Ravi K., et al.
Publicado: (2018)

Circ_0046599 Promotes the Development of Hepatocellular Carcinoma by Regulating the miR-1258/RPN2 Network
por: Fang, Quangang, et al.
Publicado: (2020)

Zeylenone Induces Mitochondrial Apoptosis and Inhibits Migration and Invasion in Gastric Cancer
por: Yang, Shuxian, et al.
Publicado: (2018)

Osthole Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration of Human Cervical Carcinoma HeLa Cells
por: Yin, Sugai, et al.
Publicado: (2021)

Downregulation of NONO induces apoptosis, suppressing growth and invasion in esophageal squamous cell carcinoma
por: Cheng, Rui, et al.
Publicado: (2018)

miR-101 Inhibiting Cell Proliferation, Migration and Invasion in Hepatocellular Carcinoma through Downregulating Girdin
por: Cao, Ke, et al.
Publicado: (2016)

FOXO3a inhibits nephroblastoma cell proliferation, migration and invasion, and induces apoptosis through downregulating the Wnt/β-catenin signaling pathway
por: Qian, Cheng, et al.
Publicado: (2021)

MicroRNA-466 inhibits cancer cell migration and invasion in hepatocellular carcinoma by indirectly mediating the downregulation of ROCK2
por: Ai, Ning, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_v7po1ptddn6olqrn365t0ouv5l