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Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis

The development of the malaria parasite, Plasmodium falciparum, in the human erythrocyte, relies on phospholipid metabolism to fulfil the massive need for membrane biogenesis. Phosphatidylcholine (PC) is the most abundant phospholipid in Plasmodium membranes. PC biosynthesis is mainly ensured by the...

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Detalles Bibliográficos
Autores principales:	Guca, Ewelina, Nagy, Gergely N., Hajdú, Fanni, Marton, Lívia, Izrael, Richard, Hoh, François, Yang, Yinshan, Vial, Henri, Vértessy, Beata G., Guichou, Jean-François, Cerdan, Rachel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060094/ https://www.ncbi.nlm.nih.gov/pubmed/30046154 http://dx.doi.org/10.1038/s41598-018-29500-9

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