Cargando…

Isosteviol Derivative Inhibits Osteoclast Differentiation and Ameliorates Ovariectomy-Induced Osteoporosis

NC-8 (ent-16-oxobeyeran-19-N-methylureido) is an isosteviol-derived analogue with multiple biological effects, including anti-inflammation and anti-bacterial activities and inhibition of HBV viral surface antigen gene expression. In this study, we explored the effects of NC-8 on the formation of ost...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tzeng, Huey-En, Huang, Po-Hao, Tsai, Chun-Hao, Tsay, Gregory J, Lee, Yi-Ju, Huang, Tsurng-Juhn, Lin, Tzu-Hung, Chiu, Ying-Ming, Wu, Yi-Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060097/ https://www.ncbi.nlm.nih.gov/pubmed/30046042 http://dx.doi.org/10.1038/s41598-018-29257-1

Ejemplares similares

Isovaleric acid ameliorates ovariectomy‐induced osteoporosis by inhibiting osteoclast differentiation
por: Cho, Kwang Min, et al.
Publicado: (2021)

Radix Paeoniae Rubra stimulates osteoclast differentiation by activation of the NF-κB and mitogen-activated protein kinase pathways
por: Tzeng, Huey-En, et al.
Publicado: (2018)

Icaritin ameliorates RANKL-mediated osteoclastogenesis and ovariectomy-induced osteoporosis
por: Huang, Jun-ming, et al.
Publicado: (2023)

Intermittent parathyroid hormone treatment affects the bone structural parameters and mechanical strength of the femoral neck after ovariectomy-induced osteoporosis in rats
por: Wang, Shun-Ping, et al.
Publicado: (2022)

Acacetin Prevents Bone Loss by Disrupting Osteoclast Formation and Promoting Type H Vessel Formation in Ovariectomy-Induced Osteoporosis
por: Lin, Xiao, et al.
Publicado: (2022)

7,8-Dihydroxyflavone modulates bone formation and resorption and ameliorates ovariectomy-induced osteoporosis
por: Xue, Fan, et al.
Publicado: (2021)

Phillyrin Prevents Ovariectomy-Induced Osteolysis by Inhibiting Osteoclast Differentiation
por: Zhang, Geng, et al.
Publicado: (2022)

Chaenomelis fructus inhibits osteoclast differentiation by suppressing NFATc1 expression and prevents ovariectomy-induced osteoporosis
por: Kim, Minsun, et al.
Publicado: (2020)

Dendrobium officinale Orchid Extract Prevents Ovariectomy-Induced Osteoporosis in Vivo and Inhibits RANKL-Induced Osteoclast Differentiation in Vitro
por: Wang, Qi, et al.
Publicado: (2018)

Deficiency of Adiponectin Protects against Ovariectomy-Induced Osteoporosis in Mice
por: Wang, Fang, et al.
Publicado: (2013)

Isosteviol prevents the development of isoprenaline-induced myocardial hypertrophy
por: Chen, Yaoxu, et al.
Publicado: (2019)

Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity
por: Huang, Jun-ming, et al.
Publicado: (2021)

Corrigendum: Dendrobium officinale Orchid Extract Prevents Ovariectomy-Induced Osteoporosis In Vivo and Inhibits RANKL-Induced Osteoclast Differentiation In Vitro
por: Wang, Qi, et al.
Publicado: (2020)

Rutin Improves Bone Histomorphometric Values by Reduction of Osteoclastic Activity in Osteoporosis Mouse Model Induced by Bilateral Ovariectomy
por: Lee, Hye-Hwa, et al.
Publicado: (2020)

Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function
por: Zhang, Yuan-Wei, et al.
Publicado: (2022)

Water Extract of Piper longum Linn Ameliorates Ovariectomy-Induced Bone Loss by Inhibiting Osteoclast Differentiation
por: Gu, Dong Ryun, et al.
Publicado: (2022)

Isosteviol sodium protects the cardiomyocyte response associated with the SIRT1/PGC‐1α pathway
por: Mei, Ying, et al.
Publicado: (2020)

Orientin suppresses osteoclastogenesis and ameliorates ovariectomy‐induced osteoporosis via suppressing ROS production
por: Zheng, Yan, et al.
Publicado: (2023)

How zoledronic acid improves osteoporosis by acting on osteoclasts
por: Wang, Biao, et al.
Publicado: (2022)

Solanum nigrum Line inhibits osteoclast differentiation and suppresses bone mineral density reduction in the ovariectomy-induced osteoporosis model
por: Kim, Jae-Hyun, et al.
Publicado: (2021)

Calcitonin Induces Bone Formation by Increasing Expression of Wnt10b in Osteoclasts in Ovariectomy-Induced Osteoporotic Rats
por: Hsiao, Chen-Yuan, et al.
Publicado: (2020)

Bioactivity Profile of the Diterpene Isosteviol and its Derivatives
por: Ullah, Asad, et al.
Publicado: (2019)

Pu-erh Tea Extract Ameliorates Ovariectomy-Induced Osteoporosis in Rats and Suppresses Osteoclastogenesis In Vitro
por: Liu, Titi, et al.
Publicado: (2017)

A cross-sectional analysis of the association between sleep duration and osteoporosis risk in adults using 2005–2010 NHANES
por: Lee, Chia-Lin, et al.
Publicado: (2021)

Membrane trafficking in osteoclasts and implications for osteoporosis
por: Ng, Pei Ying, et al.
Publicado: (2019)

Neuroprotective Effects of Isosteviol Sodium Injection on Acute Focal Cerebral Ischemia in Rats
por: Hu, Hui, et al.
Publicado: (2016)

Design and Synthesis of Isosteviol Triazole Conjugates for Cancer Therapy
por: Khaybullin, Ravil N., et al.
Publicado: (2014)

Erythrocyte Partitioning Profile of Isosteviol in Human and Rat Blood
por: Adehin, Ayorinde, et al.
Publicado: (2019)

The Finally Rewarding Search for A Cytotoxic Isosteviol Derivative
por: Heisig, Julia, et al.
Publicado: (2023)

Sanguinarine protects against ovariectomy-induced osteoporosis in mice
por: Ma, Yan, et al.
Publicado: (2017)

Therapeutic effects of isoquercetin on ovariectomy-induced osteoporosis in mice
por: Wu, Mengjing, et al.
Publicado: (2023)

Design and Synthesis of C-19 Isosteviol Derivatives as Potent and Highly Selective Antiproliferative Agents
por: Luan, Tian, et al.
Publicado: (2018)

Amaranthus mangostanus Inhibits the Differentiation of Osteoclasts and Prevents Ovariectomy-Induced Bone Loss
por: Jeong, Yeon-Hui, et al.
Publicado: (2020)

Effect of osteoporosis induced by ovariectomy on vertebral bone defect/fracture in rat
por: Shen, Geng-Yang, et al.
Publicado: (2017)

Novel supramolecular affinity materials based on (−)-isosteviol as molecular templates
por: Lohoelter, Christina, et al.
Publicado: (2013)

Mitochondriotropic and Cardioprotective Effects of Triphenylphosphonium-Conjugated Derivatives of the Diterpenoid Isosteviol
por: Testai, Lara, et al.
Publicado: (2017)

Synthesis and Biological Application of Isosteviol-Based 1,3-Aminoalcohols
por: Ozsvár, Dániel, et al.
Publicado: (2021)

Calcitonin Inhibits SDCP-Induced Osteoclast Apoptosis and Increases Its Efficacy in a Rat Model of Osteoporosis
por: Kuo, Yi-Jie, et al.
Publicado: (2012)

Class 1 integrons and plasmid-mediated multiple resistance genes of the Campylobacter species from pediatric patient of a university hospital in Taiwan
por: Chang, Yi-Chih, et al.
Publicado: (2017)

Characterization of a rabbit osteoporosis model induced by ovariectomy and glucocorticoid
por: Baofeng, Li, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_35pq5sca2hccsv96ehodjlfk20