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Autophagy activation contributes to lipid accumulation in tubular epithelial cells during kidney fibrosis

Sustained activation of autophagy and lipid accumulation in tubular epithelial cells (TECs) are both associated with the kidney fibrosis progression. Autophagy has been found involved in the lipid metabolism regulation through a bi-directional mechanism of inducing lipolysis as well as promoting lip...

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Detalles Bibliográficos
Autores principales: Yan, Qi, Song, Yuan, Zhang, Lu, Chen, Zhaowei, Yang, Cheng, Liu, Shan, Yuan, Xiaohan, Gao, Hongyu, Ding, Guohua, Wang, Huiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060103/
https://www.ncbi.nlm.nih.gov/pubmed/30062051
http://dx.doi.org/10.1038/s41420-018-0065-2