Activated platelets induce MLKL-driven neutrophil necroptosis and release of neutrophil extracellular traps in venous thrombosis

Venous thromboembolic (VTE) disease, often manifesting as deep vein thrombosis or pulmonary embolism, involves clot formation consisting of blood cells and platelets locked in plasma protein and chromatin networks. The latter derives from neutrophil extracellular traps released by dying neutrophils;...

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Detalles Bibliográficos
Autores principales: Nakazawa, Daigo, Desai, Jyaysi, Steiger, Stefanie, Müller, Susanne, Devarapu, Satish Kumar, Mulay, Shrikant R., Iwakura, Takamasa, Anders, Hans-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060161/
https://www.ncbi.nlm.nih.gov/pubmed/30062055
http://dx.doi.org/10.1038/s41420-018-0073-2

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