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The effect of pulsatile motion and cardiac-gating on reconstruction and diffusion tensor properties of the corticospinal tract

Pulsatile motion occurs in the cardiac systolic period and leads to significantly larger displacement of water molecules as it is observed during diffusion weighted image acquisition. Obvious pulsatile motion arises in the brain stem and basal ganglia and might affect the corticospinal tract. So far...

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Autores principales: Bopp, Miriam H. A., Yang, Jia, Nimsky, Christopher, Carl, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060167/
https://www.ncbi.nlm.nih.gov/pubmed/30046120
http://dx.doi.org/10.1038/s41598-018-29525-0
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author Bopp, Miriam H. A.
Yang, Jia
Nimsky, Christopher
Carl, Barbara
author_facet Bopp, Miriam H. A.
Yang, Jia
Nimsky, Christopher
Carl, Barbara
author_sort Bopp, Miriam H. A.
collection PubMed
description Pulsatile motion occurs in the cardiac systolic period and leads to significantly larger displacement of water molecules as it is observed during diffusion weighted image acquisition. Obvious pulsatile motion arises in the brain stem and basal ganglia and might affect the corticospinal tract. So far there is no consensus on the real effect of pulsatile motion on diffusion properties, diffusion tensor parameters and fiber tractography and on the role of cardiac-gating to overcome these effects. The present study aimed at detecting effects of pulsatile motion on imaging properties and reconstruction of the corticospinal tract. Non-gated and cardiac-gated data of 22 healthy subjects was acquired using clinical standard protocols and analysed with regard to effects on signal intensities, diffusion tensor properties and tractography results concerning the corticospinal tract. Analyses resulted in obvious effects of pulsatile motion on signal intensities, especially alterations in diffusion tensor properties, compensated by the application of cardiac-gating, whereas no effect on fiber tract volume was seen. Therefore, pulsatile motion and cardiac-gating should be kept in mind as critical aspects when analysing and interpreting diffusion tensor properties within the human brain, but are of minor interest when considering fiber tractography of the corticospinal tract.
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spelling pubmed-60601672018-07-31 The effect of pulsatile motion and cardiac-gating on reconstruction and diffusion tensor properties of the corticospinal tract Bopp, Miriam H. A. Yang, Jia Nimsky, Christopher Carl, Barbara Sci Rep Article Pulsatile motion occurs in the cardiac systolic period and leads to significantly larger displacement of water molecules as it is observed during diffusion weighted image acquisition. Obvious pulsatile motion arises in the brain stem and basal ganglia and might affect the corticospinal tract. So far there is no consensus on the real effect of pulsatile motion on diffusion properties, diffusion tensor parameters and fiber tractography and on the role of cardiac-gating to overcome these effects. The present study aimed at detecting effects of pulsatile motion on imaging properties and reconstruction of the corticospinal tract. Non-gated and cardiac-gated data of 22 healthy subjects was acquired using clinical standard protocols and analysed with regard to effects on signal intensities, diffusion tensor properties and tractography results concerning the corticospinal tract. Analyses resulted in obvious effects of pulsatile motion on signal intensities, especially alterations in diffusion tensor properties, compensated by the application of cardiac-gating, whereas no effect on fiber tract volume was seen. Therefore, pulsatile motion and cardiac-gating should be kept in mind as critical aspects when analysing and interpreting diffusion tensor properties within the human brain, but are of minor interest when considering fiber tractography of the corticospinal tract. Nature Publishing Group UK 2018-07-25 /pmc/articles/PMC6060167/ /pubmed/30046120 http://dx.doi.org/10.1038/s41598-018-29525-0 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Bopp, Miriam H. A.
Yang, Jia
Nimsky, Christopher
Carl, Barbara
The effect of pulsatile motion and cardiac-gating on reconstruction and diffusion tensor properties of the corticospinal tract
title The effect of pulsatile motion and cardiac-gating on reconstruction and diffusion tensor properties of the corticospinal tract
title_full The effect of pulsatile motion and cardiac-gating on reconstruction and diffusion tensor properties of the corticospinal tract
title_fullStr The effect of pulsatile motion and cardiac-gating on reconstruction and diffusion tensor properties of the corticospinal tract
title_full_unstemmed The effect of pulsatile motion and cardiac-gating on reconstruction and diffusion tensor properties of the corticospinal tract
title_short The effect of pulsatile motion and cardiac-gating on reconstruction and diffusion tensor properties of the corticospinal tract
title_sort effect of pulsatile motion and cardiac-gating on reconstruction and diffusion tensor properties of the corticospinal tract
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060167/
https://www.ncbi.nlm.nih.gov/pubmed/30046120
http://dx.doi.org/10.1038/s41598-018-29525-0
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