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Blood–brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound
Magnetic resonance-guided focused ultrasound in combination with intravenously injected microbubbles has been shown to transiently open the blood–brain barrier, and reduce beta-amyloid and tau pathology in animal models of Alzheimer’s disease. Here, we used focused ultrasound to open the blood–brain...
Autores principales: | Lipsman, Nir, Meng, Ying, Bethune, Allison J., Huang, Yuexi, Lam, Benjamin, Masellis, Mario, Herrmann, Nathan, Heyn, Chinthaka, Aubert, Isabelle, Boutet, Alexandre, Smith, Gwenn S., Hynynen, Kullervo, Black, Sandra E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060168/ https://www.ncbi.nlm.nih.gov/pubmed/30046032 http://dx.doi.org/10.1038/s41467-018-04529-6 |
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