In-Vivo Nucleus Pulposus-Specific Regulation of Adult Murine Intervertebral Disc Degeneration via Wnt/Beta-Catenin Signaling

B-Catenin, transcription factor of Wnt signaling, is promoted in patients with intervertebral disc (IVD) degeneration, but Wnt signaling decreases with aging. We hypothesize that IVD degeneration is associated with decreased Wnt signaling despite more b-Catenin. Chronic compression of tail IVDs of y...

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Detalles Bibliográficos
Autores principales: Holguin, Nilsson, Silva, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060169/
https://www.ncbi.nlm.nih.gov/pubmed/30046041
http://dx.doi.org/10.1038/s41598-018-29352-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060169/
https://www.ncbi.nlm.nih.gov/pubmed/30046041
http://dx.doi.org/10.1038/s41598-018-29352-3

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