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Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules

Mast cells (MCs) are characterized by an abundance of lysosome-like secretory granules filled with immunomodulatory compounds including histamine, cytokines, lysosomal hydrolases, MC-restricted proteases, and serglycin proteoglycans. The latter are essential for promoting the storage of other granul...

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Detalles Bibliográficos
Autores principales:	Hu Frisk, Jun Mei, Kjellén, Lena, Melo, Fabio R., Öhrvik, Helena, Pejler, Gunnar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060404/ https://www.ncbi.nlm.nih.gov/pubmed/30073001 http://dx.doi.org/10.3389/fimmu.2018.01670

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