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TLR-3 Stimulation Skews M2 Macrophages to M1 Through IFN-αβ Signaling and Restricts Tumor Progression

During tumor progression, macrophages shift their protective M1-phenotype to pro-tumorigenic M2-subtype. Therefore, conversion of M2 to M1 phenotype may be a potential therapeutic intervention. TLRs are important pathogen recognition receptors expressed by cells of the immune system. Recently, a cru...

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Detalles Bibliográficos
Autores principales:	Vidyarthi, Aurobind, Khan, Nargis, Agnihotri, Tapan, Negi, Shikha, Das, Deepjyoti K., Aqdas, Mohammad, Chatterjee, Deepyan, Colegio, Oscar R., Tewari, Manoj K., Agrewala, Javed N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060442/ https://www.ncbi.nlm.nih.gov/pubmed/30072995 http://dx.doi.org/10.3389/fimmu.2018.01650

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