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Global Stabilization of Boolean Networks to Control the Heterogeneity of Cellular Responses
Boolean networks (BNs) have been widely used as a useful model for molecular regulatory networks in systems biology. In the state space of BNs, attractors represent particular cell phenotypes. For targeted therapy of cancer, there is a pressing need to control the heterogeneity of cellular responses...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060448/ https://www.ncbi.nlm.nih.gov/pubmed/30072906 http://dx.doi.org/10.3389/fphys.2018.00774 |