Lower genomic stability of induced pluripotent stem cells reflects increased non-homologous end joining

BACKGROUND: Induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) share many common features, including similar morphology, gene expression and in vitro differentiation profiles. However, genomic stability is much lower in iPSCs than in ESCs. In the current study, we examined whethe...

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Detalles Bibliográficos
Autores principales: Zhang, Minjie, Wang, Liu, An, Ke, Cai, Jun, Li, Guochao, Yang, Caiyun, Liu, Huixian, Du, Fengxia, Han, Xiao, Zhang, Zilong, Zhao, Zitong, Pei, Duanqing, Long, Yuan, Xie, Xin, Zhou, Qi, Sun, Yingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060453/
https://www.ncbi.nlm.nih.gov/pubmed/30045759
http://dx.doi.org/10.1186/s40880-018-0313-0

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