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AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells

Development of RNA interference-based therapies with appropriate therapeutic window remains a challenge for advanced cancers. Because cancer stem cells (CSC) are responsible of sustaining the metastatic spread of the disease to distal organs and the progressive gain of resistance of advanced cancers...

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Detalles Bibliográficos
Autores principales: Rafael, Diana, Gener, Petra, Andrade, Fernanda, Seras-Franzoso, Joaquin, Montero, Sara, Fernández, Yolanda, Hidalgo, Manuel, Arango, Diego, Sayós, Joan, Florindo, Helena F., Abasolo, Ibane, Schwartz, Simó, Videira, Mafalda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060707/
https://www.ncbi.nlm.nih.gov/pubmed/29667444
http://dx.doi.org/10.1080/10717544.2018.1461276