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AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells
Development of RNA interference-based therapies with appropriate therapeutic window remains a challenge for advanced cancers. Because cancer stem cells (CSC) are responsible of sustaining the metastatic spread of the disease to distal organs and the progressive gain of resistance of advanced cancers...
Autores principales: | Rafael, Diana, Gener, Petra, Andrade, Fernanda, Seras-Franzoso, Joaquin, Montero, Sara, Fernández, Yolanda, Hidalgo, Manuel, Arango, Diego, Sayós, Joan, Florindo, Helena F., Abasolo, Ibane, Schwartz, Simó, Videira, Mafalda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060707/ https://www.ncbi.nlm.nih.gov/pubmed/29667444 http://dx.doi.org/10.1080/10717544.2018.1461276 |
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