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Phase II study of pazopanib in combination with paclitaxel in patients with metastatic melanoma

PURPOSE: This phase II study evaluated the safety and clinical activity of pazopanib, a potent and mutlitargeted tyrosine kinase inhibitor (TKI) of vascular endothelial growth factor receptors (VEGFRs)-1, -2 and -3, platelet-derived growth factor receptor (PDGFR)-α and β, and cKit, in combination wi...

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Detalles Bibliográficos
Autores principales:	Fruehauf, John P., El-Masry, Monica, Osann, Katherine, Parmakhtiar, Basmina, Yamamoto, Maki, Jakowatz, James G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Clinical Trial Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060847/ https://www.ncbi.nlm.nih.gov/pubmed/29943192 http://dx.doi.org/10.1007/s00280-018-3624-6

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