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Synthesis of unsymmetrical disulfanes bearing 1,2,4-triazine scaffold and their in vitro screening towards anti-breast cancer activity

ABSTRACT: A new series of 1,2,4-triazine unsymmetrical disulfanes were prepared and evaluated as anticancer activity compounds against MCF-7 human breast cancer cells with some of them acting as low micromolar inhibitors. Evaluation of the cytotoxicity using an MTT assay, the inhibition of [(3)H]-th...

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Detalles Bibliográficos
Autores principales: Branowska, Danuta, Ławecka, Justyna, Sobiczewski, Mariusz, Karczmarzyk, Zbigniew, Wysocki, Waldemar, Wolińska, Ewa, Olender, Ewa, Mirosław, Barbara, Perzyna, Alicja, Bielawska, Anna, Bielawski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060961/
https://www.ncbi.nlm.nih.gov/pubmed/30100632
http://dx.doi.org/10.1007/s00706-018-2206-y

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