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Synthesis of unsymmetrical disulfanes bearing 1,2,4-triazine scaffold and their in vitro screening towards anti-breast cancer activity
ABSTRACT: A new series of 1,2,4-triazine unsymmetrical disulfanes were prepared and evaluated as anticancer activity compounds against MCF-7 human breast cancer cells with some of them acting as low micromolar inhibitors. Evaluation of the cytotoxicity using an MTT assay, the inhibition of [(3)H]-th...
Autores principales: | Branowska, Danuta, Ławecka, Justyna, Sobiczewski, Mariusz, Karczmarzyk, Zbigniew, Wysocki, Waldemar, Wolińska, Ewa, Olender, Ewa, Mirosław, Barbara, Perzyna, Alicja, Bielawska, Anna, Bielawski, Krzysztof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060961/ https://www.ncbi.nlm.nih.gov/pubmed/30100632 http://dx.doi.org/10.1007/s00706-018-2206-y |
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