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Identification of novel mutations in FFPE lung adenocarcinomas using DEPArray sorting technology and next-generation sequencing

Formalin-fixed paraffin-embedded (FFPE) tissues are utilized as the standard diagnostic method in pathology laboratories. However, admixture of unwanted tissues and shortage of normal samples, which can be used to detect somatic mutation, are considered critical factors to accurately diagnose cancer...

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Detalles Bibliográficos
Autores principales: Lee, Ji Won, Shin, Jong-Yeon, Seo, Jeong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060994/
https://www.ncbi.nlm.nih.gov/pubmed/29525983
http://dx.doi.org/10.1007/s13353-018-0439-4