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SERMs Promote Anti-Inflammatory Signaling and Phenotype of CD14+ Cells

Signaling via estrogen receptors (ER) is recognized as an essential part of the immune regulation, and ER-mediated signaling is involved in autoimmune reactions. Especially ERα activation in immune cells has been suggested to skew cytokine production toward Th2/M2-type mediators, which can have prot...

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Detalles Bibliográficos
Autores principales: Polari, Lauri, Wiklund, Anu, Sousa, Sofia, Kangas, Lauri, Linnanen, Tero, Härkönen, Pirkko, Määttä, Jorma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061028/
https://www.ncbi.nlm.nih.gov/pubmed/29574654
http://dx.doi.org/10.1007/s10753-018-0763-1