An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese

AIMS/HYPOTHESIS: A genetic risk score (GRS) consisting of 53 insulin resistance variants (GRS(53)) was recently demonstrated to associate with insulin resistance in adults. We speculated that the GRS(53) might already associate with insulin resistance during childhood, and we therefore aimed to inve...

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Detalles Bibliográficos
Autores principales: Graae, Anne-Sofie, Hollensted, Mette, Kloppenborg, Julie T., Mahendran, Yuvaraj, Schnurr, Theresia M., Appel, Emil Vincent R., Rask, Johanne, Nielsen, Tenna R. H., Johansen, Mia Ø., Linneberg, Allan, Jørgensen, Marit E., Grarup, Niels, Kadarmideen, Haja N., Holst, Birgitte, Pedersen, Oluf, Holm, Jens-Christian, Hansen, Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061152/
https://www.ncbi.nlm.nih.gov/pubmed/29855666
http://dx.doi.org/10.1007/s00125-018-4640-0

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