Cargando…

Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes

AIMS/HYPOTHESIS: Islet-specific autoantibodies can predict the development of type 1 diabetes. However, it remains unclear if B cells, per se, contribute to the causal pancreatic immunopathology. We aimed to identify phenotypic signatures of disease progression among naive and memory B cell subsets...

Descripción completa

Detalles Bibliográficos
Autores principales:	Powell, Wendy E., Hanna, Stephanie J., Hocter, Claire N., Robinson, Emma, Davies, Joanne, Dunseath, Gareth J., Luzio, Stephen, Farewell, Daniel, Wen, Li, Dayan, Colin M., Price, David A., Ladell, Kristin, Wong, F. Susan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061155/ https://www.ncbi.nlm.nih.gov/pubmed/29881878 http://dx.doi.org/10.1007/s00125-018-4651-x

Ejemplares similares

Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8(+) T cells and exhibit a distinct CD95(hi) B cell phenotype
por: Hanna, Stephanie J., et al.
Publicado: (2020)

The pathophysiology of glucose intolerance in newly diagnosed, untreated T2DM
por: Dunseath, Gareth J., et al.
Publicado: (2021)

Proinsulin in the identification and risk stratification of gestational diabetes mellitus: study protocol for a prospective, longitudinal cohort study
por: Peter, Rajesh, et al.
Publicado: (2018)

Comparison of a point-of-care analyser for the determination of HbA1c with HPLC method
por: Grant, D.A., et al.
Publicado: (2017)

Brief lifestyle interventions for prediabetes in primary care: a service evaluation
por: Thatcher, Rhys, et al.
Publicado: (2022)

T cell memory revisited using single telomere length analysis
por: Roger, Laureline, et al.
Publicado: (2023)

Therapeutic inhibition of CXCR1/2: where do we stand?
por: Sitaru, Sebastian, et al.
Publicado: (2023)

Acute postprandial gut hormone, leptin, glucose and insulin responses to resistant starch in obese children: a single blind crossover study
por: Suntharesan, Jananie, et al.
Publicado: (2023)

Metabolic Implications when Employing Heavy Pre- and Post-Exercise Rapid-Acting Insulin Reductions to Prevent Hypoglycaemia in Type 1 Diabetes Patients: A Randomised Clinical Trial
por: Campbell, Matthew D., et al.
Publicado: (2014)

The superantigens SpeC and TSST-1 specifically activate TRBV12-3/12-4(+) memory T cells
por: Shepherd, Freya R., et al.
Publicado: (2023)

CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin
por: McCully, Michelle L., et al.
Publicado: (2018)

Association of asthma severity and educational attainment at age 6–7 years in a birth cohort: population-based record-linkage study
por: Evans, Annette, et al.
Publicado: (2021)

IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine
por: McLaren, James E., et al.
Publicado: (2019)

Phase II multicentre, double-blind, randomised trial of ustekinumab in adolescents with new-onset type 1 diabetes (USTEK1D): trial protocol
por: Gregory, John W, et al.
Publicado: (2021)

CD57(+) Memory T Cells Proliferate In Vivo
por: Ahmed, Raya, et al.
Publicado: (2020)

CXCR3 enables recruitment and site-specific bystander activation of memory CD8(+) T cells
por: Maurice, Nicholas J., et al.
Publicado: (2019)

Editorial: Representational states in memory: where do we stand?
por: Öztekin, Ilke, et al.
Publicado: (2015)

The Role of CXCR1, CXCR2, CXCR3, CXCR5, and CXCR6 Ligands in Molecular Cancer Processes and Clinical Aspects of Acute Myeloid Leukemia (AML)
por: Korbecki, Jan, et al.
Publicado: (2023)

Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells
por: Heinrich, Eileen L, et al.
Publicado: (2012)

Stochastic Expansions Maintain the Clonal Stability of CD8(+) T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus
por: Smith, Corinne J., et al.
Publicado: (2020)

Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis
por: Hernandez, Lorena, et al.
Publicado: (2011)

CXCR6 regulates localization of tissue-resident memory CD8 T cells to the airways
por: Wein, Alexander N., et al.
Publicado: (2019)

CXCR7 Controls Competition for Recruitment of β-Arrestin 2 in Cells Expressing Both CXCR4 and CXCR7
por: Coggins, Nathaniel L., et al.
Publicado: (2014)

The polyphenol epigallocatechin gallate lowers circulating catecholamine concentrations and alters lipid metabolism during graded exercise in man: a randomized cross-over study
por: Churm, Rachel, et al.
Publicado: (2023)

The Role of the CXCL12/CXCR4/CXCR7 Chemokine Axis in Cancer
por: Shi, Yi, et al.
Publicado: (2020)

Human Stem Cell-like Memory T Cells Are Maintained in a State of Dynamic Flux
por: Ahmed, Raya, et al.
Publicado: (2016)

Comparing Memory-Efficient Genome Assemblers on Stand-Alone and Cloud Infrastructures
por: Kleftogiannis, Dimitrios, et al.
Publicado: (2013)

Prognostic Value of CXCR2 in Breast Cancer
por: Boissière-Michot, Florence, et al.
Publicado: (2020)

CXCR2 inhibition suppresses acute and chronic pancreatic inflammation
por: Steele, Colin W, et al.
Publicado: (2015)

Memory, modelling and Marr: a commentary on Marr (1971) ‘Simple memory: a theory of archicortex’
por: Willshaw, D. J., et al.
Publicado: (2015)

Critical role for CXCR6 in NK cell-mediated antigen-specific memory to haptens and viruses
por: Paust, Silke, et al.
Publicado: (2010)

Aberrant expansion of CXCR5(+ )memory CD4 T cells in patients with systemic lupus erythematosus
por: Choi, Jin-Young, et al.
Publicado: (2014)

Type 1 diabetes patients increase CXCR4(+) and CXCR7(+) haematopoietic and endothelial progenitor cells with exercise, but the response is attenuated
por: Taylor, Guy S., et al.
Publicado: (2021)

Computer‐aided assessment of the chemokine receptors CXCR3, CXCR4 and CXCR7 expression in gallbladder carcinoma
por: Yu, Xiao, et al.
Publicado: (2020)

Human T(SCM) cell dynamics in vivo are compatible with long-lived immunological memory and stemness
por: Costa del Amo, Pedro, et al.
Publicado: (2018)

Limits of normality and symmetry in standing back shape and posture
por: Bettany-Saltikov, Josette, et al.
Publicado: (2010)

Autoreactive B cells in rheumatoid arthritis include mainly activated CXCR3(+) memory B cells and plasmablasts
por: Reijm, Sanne, et al.
Publicado: (2023)

Temporal Effects of Bariatric Surgery on Adipokines, Inflammation and Oxidative Stress in Subjects with Impaired Glucose Homeostasis at 4 Years of Follow-up
por: Min, Thinzar, et al.
Publicado: (2020)

CXCR4 and CXCR3 are two distinct prognostic biomarkers in breast cancer: Database mining for CXCR family members
por: Guo, Kaibo, et al.
Publicado: (2019)

Avidity of influenza-specific memory CD8(+) T-cell populations decays over time compromising antiviral immunity
por: Humphreys, Ian R, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_arjukam7bq7nnskq0tds55jokp