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CXCL12 gene silencing down-regulates metastatic potential via blockage of MAPK/PI3K/AP-1 signaling pathway in colon cancer

BACKGROUND: To investigate the effect of CXCL12 gene silencing on proliferation,invasion, angiogenesis and the relationship of MAPK/PI3K/AP-1 signaling pathway in colon cancer cells. METHODS: RT-PCR and Western-blot were used to detect the expression of CXCL12 mRNA and protein in four colon cancer c...

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Detalles Bibliográficos
Autores principales:	Ma, J., Su, H., Yu, B., Guo, T., Gong, Z., Qi, J., Zhao, X., Du, J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061162/ https://www.ncbi.nlm.nih.gov/pubmed/29305742 http://dx.doi.org/10.1007/s12094-017-1821-0

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