Disruption of A2AR-D2R Heteroreceptor Complexes After A2AR Transmembrane 5 Peptide Administration Enhances Cocaine Self-Administration in Rats

Antagonistic allosteric A2AR-D2R receptor-receptor interactions in heteroreceptor complexes counteract cocaine self-administration and cocaine seeking in rats as seen in biochemical and behavioral experiments. It was shown that the human A2AR transmembrane five (TM5) was part of the interface of the...

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Detalles Bibliográficos
Autores principales: Borroto-Escuela, Dasiel O., Wydra, Karolina, Li, Xiang, Rodriguez, David, Carlsson, Jens, Jastrzębska, Joanna, Filip, Malgorzata, Fuxe, Kjell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061166/
https://www.ncbi.nlm.nih.gov/pubmed/29383683
http://dx.doi.org/10.1007/s12035-018-0887-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061166/
https://www.ncbi.nlm.nih.gov/pubmed/29383683
http://dx.doi.org/10.1007/s12035-018-0887-1

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