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The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice
AIMS/HYPOTHESIS: Dipeptidyl peptidase 4 (DPP-4) inhibitors are agents designed to increase the half-life of incretins. Although they are administered orally, little is known about their effects on the gut microbiota and functions, despite the fact that some bacteria present in the gut microbiota exh...
Autores principales: | Olivares, Marta, Neyrinck, Audrey M., Pötgens, Sarah A., Beaumont, Martin, Salazar, Nuria, Cani, Patrice D., Bindels, Laure B., Delzenne, Nathalie M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061172/ https://www.ncbi.nlm.nih.gov/pubmed/29797022 http://dx.doi.org/10.1007/s00125-018-4647-6 |
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