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The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice

AIMS/HYPOTHESIS: Dipeptidyl peptidase 4 (DPP-4) inhibitors are agents designed to increase the half-life of incretins. Although they are administered orally, little is known about their effects on the gut microbiota and functions, despite the fact that some bacteria present in the gut microbiota exh...

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Detalles Bibliográficos
Autores principales: Olivares, Marta, Neyrinck, Audrey M., Pötgens, Sarah A., Beaumont, Martin, Salazar, Nuria, Cani, Patrice D., Bindels, Laure B., Delzenne, Nathalie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061172/
https://www.ncbi.nlm.nih.gov/pubmed/29797022
http://dx.doi.org/10.1007/s00125-018-4647-6

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