Cargando…

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Elevates Stimulus-Evoked Release of Dopamine in Freely-Moving Rats

Neurotrophic factors (NTFs) hold potential as disease-modifying therapies for neurodegenerative disorders like Parkinson’s disease. Glial cell line-derived neurotrophic factor (GDNF), cerebral dopamine neurotrophic factor (CDNF), and mesencephalic astrocyte-derived neurotrophic factor (MANF) have sh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Renko, Juho-Matti, Bäck, Susanne, Voutilainen, Merja H., Piepponen, T. Petteri, Reenilä, Ilkka, Saarma, Mart, Tuominen, Raimo K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061195/ https://www.ncbi.nlm.nih.gov/pubmed/29349573 http://dx.doi.org/10.1007/s12035-018-0872-8

Ejemplares similares

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Is Highly Expressed in Mouse Tissues With Metabolic Function
por: Danilova, Tatiana, et al.
Publicado: (2019)

Photoreceptor Protection by Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
por: Lu, Jianmin, et al.
Publicado: (2018)

Glial Cell Line–Derived Neurotrophic Factor Receptor Rearranged During Transfection Agonist Supports Dopamine Neurons In Vitro and Enhances Dopamine Release In Vivo
por: Mahato, Arun Kumar, et al.
Publicado: (2019)

Characterization of the Structural and Functional Determinants of MANF/CDNF in Drosophila In Vivo Model
por: Lindström, Riitta, et al.
Publicado: (2013)

MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System
por: Pakarinen, Emmi, et al.
Publicado: (2020)

GDNF Receptor Agonist Alleviates Motor Imbalance in Unilateral 6-Hydroxydopamine Model of Parkinson’s Disease
por: Renko, Juho-Matti, et al.
Publicado: (2020)

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF): An Emerging Therapeutic Target for Neurodegenerative Disorders
por: Sivakumar, Bhadrapriya, et al.
Publicado: (2023)

Emerging Roles for Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) in Pancreatic Beta Cells and Diabetes
por: Danilova, Tatiana, et al.
Publicado: (2018)

Increased Serum Levels of Mesencephalic Astrocyte-Derived Neurotrophic Factor in Subjects With Parkinson’s Disease
por: Galli, Emilia, et al.
Publicado: (2019)

Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats
por: Renko, Juho-Matti, et al.
Publicado: (2021)

An evolutionary perspective on the role of mesencephalic astrocyte-derived neurotrophic factor (MANF): At the crossroads of poriferan innate immune and apoptotic pathways
por: Sereno, Dayane, et al.
Publicado: (2017)

Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes
por: Galli, Emilia, et al.
Publicado: (2016)

Neuroplastin Modulates Anti-inflammatory Effects of MANF
por: Yagi, Takuya, et al.
Publicado: (2020)

CDNF and MANF regulate ER stress in a tissue-specific manner
por: Pakarinen, Emmi, et al.
Publicado: (2022)

MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex
por: Tseng, Kuan-Yin, et al.
Publicado: (2017)

Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress
por: Xu, Shengchun, et al.
Publicado: (2019)

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Regulates Neurite Outgrowth Through the Activation of Akt/mTOR and Erk/mTOR Signaling Pathways
por: Wen, Wen, et al.
Publicado: (2020)

Exploring the Conserved Role of MANF in the Unfolded Protein Response in Drosophila melanogaster
por: Lindström, Riitta, et al.
Publicado: (2016)

Cerebral Dopamine Neurotrophic Factor Diffuses Around the Brainstem and Does Not Undergo Anterograde Transport After Injection to the Substantia Nigra
por: Albert, Katrina, et al.
Publicado: (2019)

In vivo screening reveals interactions between Drosophila Manf and genes involved in the mitochondria and the ubiquinone synthesis pathway
por: Lindström, Riitta, et al.
Publicado: (2017)

MANF Is Neuroprotective in Early Stages of EAE, and Elevated in Spinal White Matter by Treatment With Dexamethasone
por: Nam, Jinhan, et al.
Publicado: (2021)

Evidence for an Additive Neurorestorative Effect of Simultaneously Administered CDNF and GDNF in Hemiparkinsonian Rats: Implications for Different Mechanism of Action
por: Voutilainen, Merja H., et al.
Publicado: (2017)

Human-Specific Regulation of Neurotrophic Factors MANF and CDNF by microRNAs
por: Konovalova, Julia, et al.
Publicado: (2021)

Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease
por: Bäck, Susanne, et al.
Publicado: (2013)

Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss
por: Herranen, Anni, et al.
Publicado: (2020)

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Protects Against Neuronal Apoptosis via Activation of Akt/MDM2/p53 Signaling Pathway in a Rat Model of Intracerebral Hemorrhage
por: Xu, Weilin, et al.
Publicado: (2018)

Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activity
por: Mätlik, K, et al.
Publicado: (2015)

MANF supports the inner hair cell synapse and the outer hair cell stereocilia bundle in the cochlea
por: Ikäheimo, Kuu, et al.
Publicado: (2021)

MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke
por: Tseng, Kuan-Yin, et al.
Publicado: (2018)

Pre-α-pro-GDNF and Pre-β-pro-GDNF Isoforms Are Neuroprotective in the 6-hydroxydopamine Rat Model of Parkinson's Disease
por: Penttinen, Anna-Maija, et al.
Publicado: (2018)

The role of SorLA in neurotrophic activity and complex behavior
por: Glerup, Simon, et al.
Publicado: (2013)

Cerebral dopamine neurotrophic factor protects and repairs dopamine neurons by novel mechanism
por: Lindholm, Päivi, et al.
Publicado: (2021)

Freely Behaving Mice Can Brake and Turn During Optogenetic Stimulation of the Mesencephalic Locomotor Region
por: van der Zouwen, Cornelis Immanuel, et al.
Publicado: (2021)

MANF protects human pancreatic beta cells against stress-induced cell death
por: Hakonen, Elina, et al.
Publicado: (2018)

DLC1 inhibits colon adenocarcinoma cell migration by promoting secretion of the neurotrophic factor MANF
por: Chu, Yi-Min, et al.
Publicado: (2022)

The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor
por: Eesmaa, Ave, et al.
Publicado: (2021)

Neurotrophic Factors in Parkinson’s Disease: Clinical Trials, Open Challenges and Nanoparticle-Mediated Delivery to the Brain
por: Bondarenko, Olesja, et al.
Publicado: (2021)

Cerebral dopamine neurotrophic factor–deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice
por: Lindahl, Maria, et al.
Publicado: (2019)

Neurotrophic factors for disease-modifying treatments of Parkinson's disease: gaps between basic science and clinical studies
por: Chmielarz, Piotr, et al.
Publicado: (2020)

Expression and Distribution of Mesencephalic Astrocyte-Derived Neurotrophic Factor in the Retina and Optic Nerve
por: Gao, Feng-Juan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_doislp4fd65jrq4me6hd4empbd