Dual tracer tau PET imaging reveals different molecular targets for (11)C-THK5351 and (11)C-PBB3 in the Alzheimer brain

PURPOSE: Several tau PET tracers have been developed, but it remains unclear whether they bind to the same molecular target on the heterogeneous tau pathology. In this study we evaluated the binding of two chemically different tau-specific PET tracers ((11)C-THK5351 and (11)C-PBB3) in a head-to-head...

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Detalles Bibliográficos
Autores principales: Chiotis, Konstantinos, Stenkrona, Per, Almkvist, Ove, Stepanov, Vladimir, Ferreira, Daniel, Arakawa, Ryosuke, Takano, Akihiro, Westman, Eric, Varrone, Andrea, Okamura, Nobuyuki, Shimada, Hitoshi, Higuchi, Makoto, Halldin, Christer, Nordberg, Agneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061462/
https://www.ncbi.nlm.nih.gov/pubmed/29752516
http://dx.doi.org/10.1007/s00259-018-4012-5

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