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No superior treatment for primary osteochondral defects of the talus

PURPOSE: The purpose of this systematic literature review is to detect the most effective treatment option for primary talar osteochondral defects in adults. METHODS: A literature search was performed to identify studies published from January 1996 to February 2017 using PubMed (MEDLINE), EMBASE, CD...

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Autores principales: Dahmen, Jari, Lambers, Kaj T. A., Reilingh, Mikel L., van Bergen, Christiaan J. A., Stufkens, Sjoerd. A. S., Kerkhoffs, Gino M. M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061466/
https://www.ncbi.nlm.nih.gov/pubmed/28656457
http://dx.doi.org/10.1007/s00167-017-4616-5
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author Dahmen, Jari
Lambers, Kaj T. A.
Reilingh, Mikel L.
van Bergen, Christiaan J. A.
Stufkens, Sjoerd. A. S.
Kerkhoffs, Gino M. M. J.
author_facet Dahmen, Jari
Lambers, Kaj T. A.
Reilingh, Mikel L.
van Bergen, Christiaan J. A.
Stufkens, Sjoerd. A. S.
Kerkhoffs, Gino M. M. J.
author_sort Dahmen, Jari
collection PubMed
description PURPOSE: The purpose of this systematic literature review is to detect the most effective treatment option for primary talar osteochondral defects in adults. METHODS: A literature search was performed to identify studies published from January 1996 to February 2017 using PubMed (MEDLINE), EMBASE, CDSR, DARE, and CENTRAL. Two authors separately and independently screened the search results and conducted the quality assessment using the Newcastle–Ottawa Scale. Subsequently, success rates per separate study were calculated. Studies methodologically eligible for a simplified pooling method were combined. RESULTS: Fifty-two studies with 1236 primary talar osteochondral defects were included of which forty-one studies were retrospective and eleven prospective. Two randomised controlled trials (RCTs) were identified. Heterogeneity concerning methodological nature was observed, and there was variety in reported success rates. A simplified pooling method performed for eleven retrospective case series including 317 ankles in the bone marrow stimulation group yielded a success rate of 82% [CI 78–86%]. For seven retrospective case series investigating an osteochondral autograft transfer system or an osteoperiosteal cylinder graft insertion with in total 78 included ankles the pooled success rate was calculated to be 77% [CI 66–85%]. CONCLUSIONS: For primary talar osteochondral defects, none of the treatment options showed any superiority over others. LEVEL OF EVIDENCE: IV.
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spelling pubmed-60614662018-08-09 No superior treatment for primary osteochondral defects of the talus Dahmen, Jari Lambers, Kaj T. A. Reilingh, Mikel L. van Bergen, Christiaan J. A. Stufkens, Sjoerd. A. S. Kerkhoffs, Gino M. M. J. Knee Surg Sports Traumatol Arthrosc Ankle PURPOSE: The purpose of this systematic literature review is to detect the most effective treatment option for primary talar osteochondral defects in adults. METHODS: A literature search was performed to identify studies published from January 1996 to February 2017 using PubMed (MEDLINE), EMBASE, CDSR, DARE, and CENTRAL. Two authors separately and independently screened the search results and conducted the quality assessment using the Newcastle–Ottawa Scale. Subsequently, success rates per separate study were calculated. Studies methodologically eligible for a simplified pooling method were combined. RESULTS: Fifty-two studies with 1236 primary talar osteochondral defects were included of which forty-one studies were retrospective and eleven prospective. Two randomised controlled trials (RCTs) were identified. Heterogeneity concerning methodological nature was observed, and there was variety in reported success rates. A simplified pooling method performed for eleven retrospective case series including 317 ankles in the bone marrow stimulation group yielded a success rate of 82% [CI 78–86%]. For seven retrospective case series investigating an osteochondral autograft transfer system or an osteoperiosteal cylinder graft insertion with in total 78 included ankles the pooled success rate was calculated to be 77% [CI 66–85%]. CONCLUSIONS: For primary talar osteochondral defects, none of the treatment options showed any superiority over others. LEVEL OF EVIDENCE: IV. Springer Berlin Heidelberg 2017-06-27 2018 /pmc/articles/PMC6061466/ /pubmed/28656457 http://dx.doi.org/10.1007/s00167-017-4616-5 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Ankle
Dahmen, Jari
Lambers, Kaj T. A.
Reilingh, Mikel L.
van Bergen, Christiaan J. A.
Stufkens, Sjoerd. A. S.
Kerkhoffs, Gino M. M. J.
No superior treatment for primary osteochondral defects of the talus
title No superior treatment for primary osteochondral defects of the talus
title_full No superior treatment for primary osteochondral defects of the talus
title_fullStr No superior treatment for primary osteochondral defects of the talus
title_full_unstemmed No superior treatment for primary osteochondral defects of the talus
title_short No superior treatment for primary osteochondral defects of the talus
title_sort no superior treatment for primary osteochondral defects of the talus
topic Ankle
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061466/
https://www.ncbi.nlm.nih.gov/pubmed/28656457
http://dx.doi.org/10.1007/s00167-017-4616-5
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