Reliability of In Vitro Methods Used to Measure Intrinsic Clearance of Hydrophobic Organic Chemicals by Rainbow Trout: Results of an International Ring Trial

In vitro assays are widely employed to obtain intrinsic clearance estimates used in toxicokinetic modeling efforts. However, the reliability of these methods is seldom reported. Here we describe the results of an international ring trial designed to evaluate two in vitro assays used to measure intri...

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Detalles Bibliográficos
Autores principales: Nichols, John, Fay, Kellie, Bernhard, Mary Jo, Bischof, Ina, Davis, John, Halder, Marlies, Hu, Jing, Johanning, Karla, Laue, Heike, Nabb, Diane, Schlechtriem, Christian, Segner, Helmut, Swintek, Joe, Weeks, John, Embry, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Ring Trial for Assessing Methods to Measure Chemical Clearance in Rainbow Trout
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061802/
https://www.ncbi.nlm.nih.gov/pubmed/29767801
http://dx.doi.org/10.1093/toxsci/kfy113

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