Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing

Despite the key role of the human ribosome in protein biosynthesis, little is known about the extent of sequence variation in ribosomal DNA (rDNA) or its pre-rRNA and rRNA products. We recovered ribosomal DNA segments from a single human chromosome 21 using transformation-associated recombination (T...

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Detalles Bibliográficos
Autores principales: Kim, Jung-Hyun, Dilthey, Alexander T, Nagaraja, Ramaiah, Lee, Hee-Sheung, Koren, Sergey, Dudekula, Dawood, Wood III, William H, Piao, Yulan, Ogurtsov, Aleksey Y, Utani, Koichi, Noskov, Vladimir N, Shabalina, Svetlana A, Schlessinger, David, Phillippy, Adam M, Larionov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061828/
https://www.ncbi.nlm.nih.gov/pubmed/29788454
http://dx.doi.org/10.1093/nar/gky442

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