Cargando…
Circular permutation profiling by deep sequencing libraries created using transposon mutagenesis
Deep mutational scanning has been used to create high-resolution DNA sequence maps that illustrate the functional consequences of large numbers of point mutations. However, this approach has not yet been applied to libraries of genes created by random circular permutation, an engineering strategy th...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061844/ https://www.ncbi.nlm.nih.gov/pubmed/29912470 http://dx.doi.org/10.1093/nar/gky255 |