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MIRA: an R package for DNA methylation-based inference of regulatory activity
SUMMARY: DNA methylation contains information about the regulatory state of the cell. MIRA aggregates genome-scale DNA methylation data into a DNA methylation profile for a given region set with shared biological annotation. Using this profile, MIRA infers and scores the collective regulatory activi...
Autores principales: | Lawson, John T, Tomazou, Eleni M, Bock, Christoph, Sheffield, Nathan C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061852/ https://www.ncbi.nlm.nih.gov/pubmed/29506020 http://dx.doi.org/10.1093/bioinformatics/bty083 |
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