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Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF
Vitally important for controlling gene expression in eukaryotes and prokaryotes, the deprotection of mRNA 5′ termini is governed by enzymes whose activity is modulated by interactions with ancillary factors. In Escherichia coli, 5′-end-dependent mRNA degradation begins with the generation of monopho...
Autores principales: | Gao, Ang, Vasilyev, Nikita, Luciano, Daniel J, Levenson-Palmer, Rose, Richards, Jamie, Marsiglia, William M, Traaseth, Nathaniel J, Belasco, Joel G, Serganov, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061855/ https://www.ncbi.nlm.nih.gov/pubmed/29733359 http://dx.doi.org/10.1093/nar/gky327 |
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