A functional type II-A CRISPR–Cas system from Listeria enables efficient genome editing of large non-integrating bacteriophage

CRISPR–Cas systems provide bacteria with adaptive immunity against invading DNA elements including bacteriophages and plasmids. While CRISPR technology has revolutionized eukaryotic genome engineering, its application to prokaryotes and their viruses remains less well established. Here we report the...

Descripción completa

Detalles Bibliográficos
Autores principales: Hupfeld, Mario, Trasanidou, Despoina, Ramazzini, Livia, Klumpp, Jochen, Loessner, Martin J, Kilcher, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061871/
https://www.ncbi.nlm.nih.gov/pubmed/30053228
http://dx.doi.org/10.1093/nar/gky544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061871/
https://www.ncbi.nlm.nih.gov/pubmed/30053228
http://dx.doi.org/10.1093/nar/gky544

Ejemplares similares