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Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury

Chondroitinase ABC is a promising preclinical therapy that promotes functional neuroplasticity after CNS injury by degrading extracellular matrix inhibitors. Efficient delivery of chondroitinase ABC to the injured mammalian spinal cord can be achieved by viral vector transgene delivery. This approac...

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Detalles Bibliográficos
Autores principales:	Burnside, Emily R, De Winter, Fred, Didangelos, Athanasios, James, Nicholas D, Andreica, Elena-Cristina, Layard-Horsfall, Hugo, Muir, Elizabeth M, Verhaagen, Joost, Bradbury, Elizabeth J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061881/ https://www.ncbi.nlm.nih.gov/pubmed/29912283 http://dx.doi.org/10.1093/brain/awy158

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