The conserved stem-loop II structure at the 3' untranslated region of Japanese encephalitis virus genome is required for the formation of subgenomic flaviviral RNA

Flaviviruses accumulate abundant subgenomic RNA (sfRNA) in infected cells. It has been reported that sfRNA results from stalling of host 5’-to-3’ exoribonuclease XRN1 at the highly structured RNA of the 3’ untranslated region (UTR). Although XRN1 digestion of a 3’-terminal 800-nt RNA could stall at...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Shiuan, Fan, Yi-Hsin, Tien, Chih-Feng, Yueh, Andrew, Chang, Ruey-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062100/
https://www.ncbi.nlm.nih.gov/pubmed/30048535
http://dx.doi.org/10.1371/journal.pone.0201250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062100/
https://www.ncbi.nlm.nih.gov/pubmed/30048535
http://dx.doi.org/10.1371/journal.pone.0201250

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