2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm

The human whipworm Trichuris trichiura is a parasite that infects around 500 million people globally, with consequences including damage to physical growth and educational performance. Current drugs such as mebendazole have a notable lack of efficacy against whipworm, compared to other soil-transmit...

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Detalles Bibliográficos
Autores principales: Partridge, Frederick A., Forman, Ruth, Willis, Nicky J., Bataille, Carole J. R., Murphy, Emma A., Brown, Anwen E., Heyer-Chauhan, Narinder, Marinič, Bruno, Sowood, Daniel J. C., Wynne, Graham M., Else, Kathryn J., Russell, Angela J., Sattelle, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062138/
https://www.ncbi.nlm.nih.gov/pubmed/29995893
http://dx.doi.org/10.1371/journal.pntd.0006487

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