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Brucellosis as the Cause of Non-Viral Bacterial Hepatitis: A Case Report

BACKGROUND: Brucellosis can lead to different clinical pictures such as hepatomegaly, granulomatous liver disease, hepatic abscess, and it can cause mild hepatic transaminase elevation in the laboratory investigations. CASE REPORT: We found out that the etiologic agent was Brucella in our two cases...

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Autores principales: Çavuş, Bilger, Çaydaşı, Özge, Aktan, Ahmet, Ayaz, Ercan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062275/
https://www.ncbi.nlm.nih.gov/pubmed/30087732
http://dx.doi.org/10.3889/oamjms.2018.198
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author Çavuş, Bilger
Çaydaşı, Özge
Aktan, Ahmet
Ayaz, Ercan
author_facet Çavuş, Bilger
Çaydaşı, Özge
Aktan, Ahmet
Ayaz, Ercan
author_sort Çavuş, Bilger
collection PubMed
description BACKGROUND: Brucellosis can lead to different clinical pictures such as hepatomegaly, granulomatous liver disease, hepatic abscess, and it can cause mild hepatic transaminase elevation in the laboratory investigations. CASE REPORT: We found out that the etiologic agent was Brucella in our two cases admitted with acute hepatitis presentation in the investigations conducted. Liver transaminases were as follows for case 1 and case 2; AST: 306/187U/L, ALT: 368/312U/L, ALP: 355/264U/L, GGT: 116/197U/L, LDH: 887/549U/L, respectively. Sacroiliitis also accompanied the clinical picture in our first case. Our patients showed clinical and laboratory improvement with rifampicin, doxycycline, (additional streptomycin for 21 days in the patient with sacroiliitis) treatment. CONCLUSION: Brucellosis which may manifest as a clinical picture regarding numerous medical branches should be considered in case of acute hepatitis, especially in endemic regions, along with viral hepatitis.
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spelling pubmed-60622752018-08-07 Brucellosis as the Cause of Non-Viral Bacterial Hepatitis: A Case Report Çavuş, Bilger Çaydaşı, Özge Aktan, Ahmet Ayaz, Ercan Open Access Maced J Med Sci Case Report BACKGROUND: Brucellosis can lead to different clinical pictures such as hepatomegaly, granulomatous liver disease, hepatic abscess, and it can cause mild hepatic transaminase elevation in the laboratory investigations. CASE REPORT: We found out that the etiologic agent was Brucella in our two cases admitted with acute hepatitis presentation in the investigations conducted. Liver transaminases were as follows for case 1 and case 2; AST: 306/187U/L, ALT: 368/312U/L, ALP: 355/264U/L, GGT: 116/197U/L, LDH: 887/549U/L, respectively. Sacroiliitis also accompanied the clinical picture in our first case. Our patients showed clinical and laboratory improvement with rifampicin, doxycycline, (additional streptomycin for 21 days in the patient with sacroiliitis) treatment. CONCLUSION: Brucellosis which may manifest as a clinical picture regarding numerous medical branches should be considered in case of acute hepatitis, especially in endemic regions, along with viral hepatitis. Republic of Macedonia 2018-05-17 /pmc/articles/PMC6062275/ /pubmed/30087732 http://dx.doi.org/10.3889/oamjms.2018.198 Text en Copyright: © 2018 Bilger Çavuş, Özge Çaydaşı, Ahmet Aktan, Ercan Ayaz http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
spellingShingle Case Report
Çavuş, Bilger
Çaydaşı, Özge
Aktan, Ahmet
Ayaz, Ercan
Brucellosis as the Cause of Non-Viral Bacterial Hepatitis: A Case Report
title Brucellosis as the Cause of Non-Viral Bacterial Hepatitis: A Case Report
title_full Brucellosis as the Cause of Non-Viral Bacterial Hepatitis: A Case Report
title_fullStr Brucellosis as the Cause of Non-Viral Bacterial Hepatitis: A Case Report
title_full_unstemmed Brucellosis as the Cause of Non-Viral Bacterial Hepatitis: A Case Report
title_short Brucellosis as the Cause of Non-Viral Bacterial Hepatitis: A Case Report
title_sort brucellosis as the cause of non-viral bacterial hepatitis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062275/
https://www.ncbi.nlm.nih.gov/pubmed/30087732
http://dx.doi.org/10.3889/oamjms.2018.198
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