The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth

Glioblastoma (GBM) is the most aggressive and an incurable type of brain cancer. Human cytomegalovirus (HCMV) DNA and encoded proteins, including the chemokine receptor US28, have been detected in GBM tumors. US28 displays constitutive activity and is able to bind several human chemokines, leading t...

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Detalles Bibliográficos
Autores principales: Heukers, Raimond, Fan, Tian Shu, de Wit, Raymond H., van Senten, Jeffrey R., De Groof, Timo W. M., Bebelman, Maarten P., Lagerweij, Tonny, Vieira, Joao, de Munnik, Sabrina M., Smits-de Vries, Laura, van Offenbeek, Jody, Rahbar, Afsar, van Hoorick, Diane, Söderberg-Naucler, Cecilia, Würdinger, Thomas, Leurs, Rob, Siderius, Marco, Vischer, Henry F., Smit, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062493/
https://www.ncbi.nlm.nih.gov/pubmed/29706656
http://dx.doi.org/10.1038/s41388-018-0255-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062493/
https://www.ncbi.nlm.nih.gov/pubmed/29706656
http://dx.doi.org/10.1038/s41388-018-0255-7

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