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The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth
Glioblastoma (GBM) is the most aggressive and an incurable type of brain cancer. Human cytomegalovirus (HCMV) DNA and encoded proteins, including the chemokine receptor US28, have been detected in GBM tumors. US28 displays constitutive activity and is able to bind several human chemokines, leading t...
Autores principales: | Heukers, Raimond, Fan, Tian Shu, de Wit, Raymond H., van Senten, Jeffrey R., De Groof, Timo W. M., Bebelman, Maarten P., Lagerweij, Tonny, Vieira, Joao, de Munnik, Sabrina M., Smits-de Vries, Laura, van Offenbeek, Jody, Rahbar, Afsar, van Hoorick, Diane, Söderberg-Naucler, Cecilia, Würdinger, Thomas, Leurs, Rob, Siderius, Marco, Vischer, Henry F., Smit, Martine J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062493/ https://www.ncbi.nlm.nih.gov/pubmed/29706656 http://dx.doi.org/10.1038/s41388-018-0255-7 |
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