Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1

Genetic, epigenetic, and environmental factors contribute to the multifactorial disorder progressive supranuclear palsy (PSP). Here, we study epigenetic changes by genome-wide analysis of DNA from postmortem tissue of forebrains of patients and controls and detect significant (P < 0.05) methylati...

Descripción completa

Detalles Bibliográficos
Autores principales: Weber, Axel, Schwarz, Sigrid C., Tost, Jörg, Trümbach, Dietrich, Winter, Pia, Busato, Florence, Tacik, Pawel, Windhorst, Anita C., Fagny, Maud, Arzberger, Thomas, McLean, Catriona, van Swieten, John C., Schwarz, Johannes, Vogt Weisenhorn, Daniela, Wurst, Wolfgang, Adhikary, Till, Dickson, Dennis W., Höglinger, Günter U., Müller, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062504/
https://www.ncbi.nlm.nih.gov/pubmed/30050033
http://dx.doi.org/10.1038/s41467-018-05325-y

Ejemplares similares

Ejemplares similares