Cargando…

Intracellular oligonucleotide delivery using the cell penetrating peptide Xentry

The current study investigated the use of two cationic peptides, Xentry-KALA (XK) and Xentry-Protamine (XP), for intracellular delivery of Connexin43 antisense oligonucleotides (Cx43AsODN). The charge and size of Cx43AsODN:XK and Cx43AsODN:XP complexes was determined by Zetasizer analysis. The earli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coutinho, Frazer P., Green, Colin R., Rupenthal, Ilva D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062516/ https://www.ncbi.nlm.nih.gov/pubmed/30050146 http://dx.doi.org/10.1038/s41598-018-29556-7

Ejemplares similares

Xentry-Gap19 inhibits Connexin43 hemichannel opening especially during hypoxic injury
por: Coutinho, Frazer P., et al.
Publicado: (2020)

The tetrapeptide core of the carrier peptide Xentry is cell-penetrating: novel activatable forms of Xentry
por: Montrose, Kristopher, et al.
Publicado: (2014)

Xentry, a new class of cell-penetrating peptide uniquely equipped for delivery of drugs
por: Montrose, Kristopher, et al.
Publicado: (2013)

mRNA transfection by a Xentry-protamine cell-penetrating peptide is enhanced by TLR antagonist E6446
por: Bell, Glenn D., et al.
Publicado: (2018)

Delivery of therapeutic oligonucleotides with cell penetrating peptides()
por: Boisguérin, Prisca, et al.
Publicado: (2015)

Cell-Penetrating Peptides to Enhance Delivery of Oligonucleotide-Based Therapeutics
por: McClorey, Graham, et al.
Publicado: (2018)

Delivery of cell-penetrating peptide-peptide nucleic acid conjugates by assembly on an oligonucleotide scaffold
por: Zhao, Xing-Liang, et al.
Publicado: (2015)

Cell Penetrating Peptides Used in Delivery of Therapeutic Oligonucleotides Targeting Hepatitis B Virus
por: Ndeboko, Bénédicte, et al.
Publicado: (2020)

Connexin therapeutics: blocking connexin hemichannel pores is distinct from blocking pannexin channels or gap junctions
por: Acosta, Monica L., et al.
Publicado: (2020)

Delivery of antisense oligonucleotide using polyethylenimine-based lipid nanoparticle modified with cell penetrating peptide
por: Yang, Shuang, et al.
Publicado: (2019)

Versatility of cell-penetrating peptides for intracellular delivery of siRNA
por: Singh, Tejinder, et al.
Publicado: (2018)

The Utilization of Cell-Penetrating Peptides in the Intracellular Delivery of Viral Nanoparticles
por: Váňová, Jana, et al.
Publicado: (2019)

Cell penetrating peptide conjugates of steric block oligonucleotides()
por: Lebleu, Bernard, et al.
Publicado: (2008)

Intracellular Delivery of Proteins with Cell-Penetrating Peptides for Therapeutic Uses in Human Disease
por: Dinca, Ana, et al.
Publicado: (2016)

Intracellular Delivery of Molecular Cargo Using Cell-Penetrating Peptides and the Combination Strategies
por: Li, Hua, et al.
Publicado: (2015)

Advances in intracellular delivery through supramolecular self-assembly of oligonucleotides and peptides
por: Kim, Jeonghwan, et al.
Publicado: (2019)

Mechanistic studies of intracellular delivery of proteins by cell-penetrating peptides in cyanobacteria
por: Liu, Betty R, et al.
Publicado: (2013)

Intracellular Delivery of Nanoparticles and DNAs by IR9 Cell-penetrating Peptides
por: Liu, Betty R., et al.
Publicado: (2013)

Magnetic Nanoparticle Assisted Self-assembly of Cell Penetrating Peptides-Oligonucleotides Complexes for Gene Delivery
por: Dowaidar, Moataz, et al.
Publicado: (2017)

PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation
por: Ezzat, Kariem, et al.
Publicado: (2011)

Tonabersat Inhibits Connexin43 Hemichannel Opening and Inflammasome Activation in an In Vitro Retinal Epithelial Cell Model of Diabetic Retinopathy
por: Lyon, Heather, et al.
Publicado: (2020)

Role of Cell-Penetrating Peptides in Intracellular Delivery of Peptide Nucleic Acids Targeting Hepadnaviral Replication
por: Ndeboko, Bénédicte, et al.
Publicado: (2017)

Enhancing Antisense Oligonucleotide-Based Therapeutic Delivery with DG9, a Versatile Cell-Penetrating Peptide
por: Haque, Umme Sabrina, et al.
Publicado: (2023)

Enhancing the Effectiveness of Oligonucleotide Therapeutics Using Cell-Penetrating Peptide Conjugation, Chemical Modification, and Carrier-Based Delivery Strategies
por: Anwar, Saeed, et al.
Publicado: (2023)

Human DMBT1-Derived Cell-Penetrating Peptides for Intracellular siRNA Delivery
por: Tuttolomondo, Martina, et al.
Publicado: (2017)

Differential Action of Connexin Hemichannel and Pannexin Channel Therapeutics for Potential Treatment of Retinal Diseases
por: Mat Nor, Mohd N., et al.
Publicado: (2021)

Development of a novel stability indicating RP-HPLC method for quantification of Connexin43 mimetic peptide and determination of its degradation kinetics in biological fluids
por: Bisht, Rohit, et al.
Publicado: (2017)

A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery
por: Hoffmann, Katrin, et al.
Publicado: (2018)

The Potential Role of Cell Penetrating Peptides in the Intracellular Delivery of Proteins for Therapy of Erythroid Related Disorders
por: Papadopoulou, Lefkothea C., et al.
Publicado: (2013)

Cell Penetrating Peptides in the Delivery of Biopharmaceuticals
por: Munyendo, Were LL, et al.
Publicado: (2012)

Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity
por: Wu, Rebecca P., et al.
Publicado: (2007)

Antimicrobial Peptides and Cell-Penetrating Peptides for Treating Intracellular Bacterial Infections
por: Buccini, Danieli F., et al.
Publicado: (2021)

Intracellular delivery of cell-penetrating peptide-transcriptional factor fusion protein and its role in selective osteogenesis
por: Suh, Jin Sook, et al.
Publicado: (2014)

Investigation of enhanced intracellular delivery of nanomaterials modified with novel cell-penetrating zwitterionic peptide-lipid derivatives
por: Sugimoto, Yuri, et al.
Publicado: (2023)

Formulation Considerations for the Management of Dry Eye Disease
por: Agarwal, Priyanka, et al.
Publicado: (2021)

Engineered phage with cell-penetrating peptides for intracellular bacterial infections
por: Zhao, Min, et al.
Publicado: (2023)

Surface modulation of extracellular vesicles with cell-penetrating peptide-conjugated lipids for improvement of intracellular delivery to endothelial cells
por: Huang, Tianwei, et al.
Publicado: (2023)

Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo
por: Bazaz, Safa, et al.
Publicado: (2021)

Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery
por: Wolfe, Justin M., et al.
Publicado: (2018)

Delivery of antisense oligonucleotides for splice‐correction of androgen receptor pre‐mRNA in castration‐resistant prostate cancer models using cell‐penetrating peptides
por: Luna Velez, Maria V., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_as3g7332btgisuaaufhsiin239