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Automated analysis of lipid drug-response markers by combined fast and high-resolution whole cell MALDI mass spectrometry biotyping

Recent advances in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry have enabled whole cell-MALDI mass spectrometry biotyping of drug-treated cultured cells for rapid monitoring of known abundant pharmacodynamic protein markers such as polyacetylated histones. In contrast, gener...

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Detalles Bibliográficos
Autores principales: Weigt, David, Sammour, Denis A., Ulrich, Timon, Munteanu, Bogdan, Hopf, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062520/
https://www.ncbi.nlm.nih.gov/pubmed/30050068
http://dx.doi.org/10.1038/s41598-018-29677-z

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