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Comparative genomics of Mycobacterium africanum Lineage 5 and Lineage 6 from Ghana suggests distinct ecological niches

Mycobacterium africanum (Maf) causes a substantial proportion of human tuberculosis in some countries of West Africa, but little is known on this pathogen. We compared the genomes of 253 Maf clinical isolates from Ghana, including N = 175 Lineage 5 (L5) and N = 78 Lineage 6 (L6). We found that the g...

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Detalles Bibliográficos
Autores principales: Otchere, Isaac Darko, Coscollá, Mireia, Sánchez-Busó, Leonor, Asante-Poku, Adwoa, Brites, Daniela, Loiseau, Chloe, Meehan, Conor, Osei-Wusu, Stephen, Forson, Audrey, Laryea, Clement, Yahayah, Abdallah Iddrisu, Baddoo, Akosua, Ansa, Gloria Akosua, Aboagye, Samuel Yaw, Asare, Prince, Borrell, Sonia, Gehre, Florian, Beckert, Patrick, Kohl, Thomas A., N’dira, Sanoussi, Beisel, Christian, Antonio, Martin, Niemann, Stefan, de Jong, Bouke C., Parkhill, Julian, Harris, Simon R., Gagneux, Sebastien, Yeboah-Manu, Dorothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062541/
https://www.ncbi.nlm.nih.gov/pubmed/30050166
http://dx.doi.org/10.1038/s41598-018-29620-2