Glucose promotes cell growth by suppressing branched-chain amino acid degradation

Glucose and branched-chain amino acids (BCAAs) are essential nutrients and key determinants of cell growth and stress responses. High BCAA level inhibits glucose metabolism but reciprocal regulation of BCAA metabolism by glucose has not been demonstrated. Here we show that glucose suppresses BCAA ca...

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Detalles Bibliográficos
Autores principales: Shao, Dan, Villet, Outi, Zhang, Zhen, Choi, Sung Won, Yan, Jie, Ritterhoff, Julia, Gu, Haiwei, Djukovic, Danijel, Christodoulou, Danos, Kolwicz, Stephen C., Raftery, Daniel, Tian, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062555/
https://www.ncbi.nlm.nih.gov/pubmed/30050148
http://dx.doi.org/10.1038/s41467-018-05362-7

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