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4-(Hydroxymethyl)catechol Extracted From Fungi in Marine Sponges Attenuates Rheumatoid Arthritis by Inhibiting PI3K/Akt/NF-κB Signaling

Rheumatoid arthritis (RA) is a progressive autoimmune disease specific to synovial joints; it causes joint damage and other systemic abnormalities, thereby leading to physical disability and early mortality. Marine sponge-derived fungi, Pestalotiopsis sp., secrete immunosuppressive compounds in the...

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Detalles Bibliográficos
Autores principales:	Lee, Jong Y., Kim, Geum J., Choi, Jin K., Choi, Young-Ae, Jeong, Na-Hee, Park, Pil-Hoon, Choi, Hyukjae, Kim, Sang-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062625/ https://www.ncbi.nlm.nih.gov/pubmed/30079020 http://dx.doi.org/10.3389/fphar.2018.00726

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