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Antibody-mediated oral delivery of therapeutic DNA for type 2 diabetes mellitus

BACKGROUND: Diabetes mellitus (DM) is a chronic progressive metabolic disease that involves uncontrolled elevation of blood glucose levels. Among various therapeutic approaches, GLP-1 prevents type 2 diabetes mellitus (T2DM) patients from experiencing hyperglycemic episodes. However, the short half-...

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Detalles Bibliográficos
Autores principales: Cha, Seungbin, Lee, Sun Hwa, Kang, Sung Hun, Hasan, Mohammad Nazmul, Kim, Young Jun, Cho, Sungpil, Lee, Yong-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062860/
https://www.ncbi.nlm.nih.gov/pubmed/30065848
http://dx.doi.org/10.1186/s40824-018-0129-7