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The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer
BACKGROUND: The PAM50-based (Prosigna) risk of recurrence (ROR) score and intrinsic subtypes are prognostic for women with high-risk breast cancer. We investigate the predictive ability of Prosigna regarding the effectiveness of cyclophosphamide-based adjuvant chemotherapy in premenopausal patients...
Autores principales: | Jensen, Maj-Britt, Lænkholm, Anne-Vibeke, Nielsen, Torsten O., Eriksen, Jens Ole, Wehn, Pernille, Hood, Tressa, Ram, Namratha, Buckingham, Wesley, Ferree, Sean, Ejlertsen, Bent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062869/ https://www.ncbi.nlm.nih.gov/pubmed/30053900 http://dx.doi.org/10.1186/s13058-018-1012-0 |
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