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Phenformin alone or combined with gefitinib inhibits bladder cancer via AMPK and EGFR pathways

BACKGROUND: In previous studies, we have shown that the combination of metformin and gefitinib inhibits the growth of bladder cancer cells. Here we examined whether the metformin analogue phenformin, either used alone or in combination with gefitinib, could inhibit growth of bladder cancer cells. ME...

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Detalles Bibliográficos
Autores principales: Huang, Yanjun, Zhou, Sichun, He, Caimei, Deng, Jun, Tao, Ting, Su, Qiongli, Darko, Kwame Oteng, Peng, Mei, Yang, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062982/
https://www.ncbi.nlm.nih.gov/pubmed/30053908
http://dx.doi.org/10.1186/s40880-018-0319-7